24-Hour Urine Metamachines Excretion Test

The 24-Hour Urine Metanephrine Excretion Test measures the total amount of metanephrines—biochemical by-products of the catecholamines adrenaline and noradrenaline—eliminated in urine over a full 24-hour collection period. These compounds are produced when the adrenal glands secrete catecholamines, and elevated urinary metanephrine levels may suggest the presence of an adrenal or paraganglionic tumour such as a Pheochromocytoma. This non-invasive test is crucial for diagnosing hormonally active adrenal gland disorders, especially when symptoms like unexplained high blood pressure, rapid heartbeat, sweating, or headaches occur. The patient must collect all urine over 24 hours, properly store the sample, and follow pre-test instructions regarding diet, medications, and activity to ensure accurate results.